Genetically modified endothelial cells are grown on the inside surface of a cylindrical hollow fiber with an internal diameter of 200 μm and a length of 15 cm. This bioreactor is being used to remove toxin A from plasma at 37°C. These cells carry on their surface an enzyme that instantly converts toxin A into a harmless substance. The plasma flows through the hollow fiber at the rate of 0.75 cm3min−1. If toxin A enters the bioreactor at a concentration of 0.01 mol L−1, find the toxin concentration at the outlet of the hollow fiber bioreactor. The toxin has a MW of 785 g mol−1.
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