Frog poison. Batrachotoxin (BTX) is a steroidal alkaloid from the skin of Phyllobates terribilis, a poisonous Colombian frog (the source of the poison used on blowgun darts). In the presence of BTX,...


Frog poison. Batrachotoxin (BTX) is a steroidal alkaloid from the skin<br>of Phyllobates terribilis, a poisonous Colombian frog (the source of<br>the poison used on blowgun darts). In the presence of BTX, Na+Na*<br>channels in an excised patch stay persistently open when the<br>membrane is depolarized. They close when the membrane is<br>repolarized. Which transition is blocked by BTX?<br>

Extracted text: Frog poison. Batrachotoxin (BTX) is a steroidal alkaloid from the skin of Phyllobates terribilis, a poisonous Colombian frog (the source of the poison used on blowgun darts). In the presence of BTX, Na+Na* channels in an excised patch stay persistently open when the membrane is depolarized. They close when the membrane is repolarized. Which transition is blocked by BTX?

Jun 11, 2022
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