Figure 14.4 is from a study to determine the association between the concentration of prostate specific antigen (PSA) at an age of 40–55 and the subsequent risk of prostate cancer metastasis and...

Figure 14.4 is from a study to determine the association between the concentration of prostate specific antigen (PSA) at an age of 40–55 and the subsequent risk of prostate cancer metastasis and mortality in an unscreened population, in order to evaluate when to start screening for prostate cancer and whether rescreening could be risk stratified. The figure shows the proportion of deaths or metastases from prostate cancer captured by respective categories of increased concentrations of PSA for the same individuals at age 45–49 and 51–55. Compare the proportions and the precision of the CIs for death and metastases for the highest tenth of PSA in each age group.