Design a tissue engineered system for the delivery to the systemic circulation of human growth hormone (hGH). hGH has a molecular weight of 22,000 g mol−1. Assume that the hGH has an apparent...

Design a tissue engineered system for the delivery to the systemic circulation of human growth hormone (hGH). hGH has a molecular weight of 22,000 g mol−1. Assume that the hGH has an apparent distribution volume in the body of 30 L. Assume that autologous cells were transfected with a recombinant gene for hGH. The production rate of hGH from these cells is
 hGH should be maintained at about 10 ng mL−1. Assume hGH has a half-life in the body of about 2.3 h. Describe your system for delivering hGH and carefully state all assumptions. How many cells will be required for the delivery of the hGH?