critically appraise the reported experimental design and statisticalanalysis methods for the article: Hardy JL, Nelson RA, Thomason ME, Sternberg DA, Katovich K, Farzin F, et al...

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Answered Same DayAug 06, 2023

Answer To: critically appraise the reported experimental design and statisticalanalysis methods for the...

Pratibha answered on Aug 07 2023
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Enhancing Cognitive Abilities with Comprehensive Training: A Large, Online, Randomized, Active-Controlled Trial
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Q1] Answer:
The authors aimed to assess the effectiveness of a specific cognitive t
raining program compared to an engaging control activity (crossword puzzles) through a large randomized trial. They sought to demonstrate that the cognitive training program would lead to broader improvements in various cognitive skills, as measured by neuropsychological tests and participant-reported outcomes, surpassing the benefits of the active control group.
Q2] Answer:
Experimental Units:
· The experimental units are individuals who were recruited from the Lumosity website.
· A total of 11,470 individuals consented to participate in the study and completed a baseline assessment.
Treatment Factors:
· The primary treatment factor is the type of cognitive activity: cognitive training using the Lumosity program (treatment group) and crossword puzzles (control group).
· Both treatment and control groups were instructed to engage in their respective activities (cognitive training or crossword puzzles) for 10 weeks, with daily participation reminders.
Response Variables:
· The primary response variable is change in aggregate cognitive performance, measured by the Grand Index, a composite score derived from seven neuropsychological tests.
· Secondary response variables include changes in performance on individual subtests within the neuropsychological battery and participant-reported outcomes related to cognitive failures, successes, and emotional status.
Key Features of the Experimental Protocol:
· Participants were randomized into either the cognitive training group or the crossword puzzles control group.
· Random assignment to treatment conditions occurred after a pre-test assessment.
· Participants were between the ages of 18 and 80 and had created an account on the Lumosity website.
· The cognitive training group used the Lumosity program, which included daily sessions of five cognitive training tasks targeting various cognitive abilities.
· The crossword puzzles control group completed as many crossword puzzles as possible in a 15-minute daily session.
· Compliance with the study protocol was assessed based on the number of active days participants engaged with their assigned activity.
· The primary outcome...
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