Could you prove cause and effect using something like Koch’s postulates if you could not cultivate the organism you suspect is causing the disease? What type of approach would you use? Are there...

Could you prove cause and effect using something like Koch’s postulates if you could not cultivate the organism you suspect is causing the disease? What type of approach would you use?

Are there features of a disease that allow human subjects to be used to satisfy Koch’s postulates? What are they?