Consider a Phase II clinical trial designed to investigate the effectiveness of a new drug to reduce symptoms of asthma in children. A total of n=10 participants is randomized to receive either the...

Consider a Phase II clinical trial designed to investigate the effectiveness of a new drug to reduce symptoms of asthma in children. A total of n=10 participants is randomized to receive either the new drug or a placebo. Participants are asked to record the number of episodes of shortness of breath over a 1week period following receipt of the assigned treatment. The data are shown below.

Placebo: 7,5,6,4,12

New Drug: 3,6,4,2,1
Is there a difference in the number of episodes of shortness of breath over the one-week period in participants receiving the new drug as compared to those receiving the placebo? By inspection, it appears that participants receiving the placebo have more episodes of shortness of breath, but is this statistically significant?
Use Wilcoxon Signed Ranked Test.