Coal miners inhale large quantities of fine coal dust when they are working in the mines. Over the years, the dust irritates their alveolar surfaces resulting in inflammation and then development of...



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Coal miners inhale large quantities of fine coal dust when they are working in the mines.<br>Over the years, the dust irritates their alveolar surfaces resulting in inflammation and<br>then development of scar tissue (a tough, stiff, thick, fibrous tissue) within the lung<br>walls.<br>Answer the following questions based on a coal miner who has developed very<br>extensive and severe scar tissue in their lungs.<br>1. Define compliance.<br>2. Would coal miners have high or low lung compliance? Explain.<br>3. What happens to the skeletal muscle force required to generate a normal TV?<br>4. Given your answer to #3, with this very severe situation, can skeletal muscle<br>continue indefinitely to generate the required force? Why or why not? And if not,<br>then what change in TV occurs?<br>5. Explain what happens to alveolar ventilation.<br>6. What happens to arterial blood Po2 levels? Explain, and be sure to include which<br>variable(s) of Fick's law are altered.<br>7. What happens to arterial blood hemoglobin saturation (% HbO2)? Explain.<br>8. What happens to arterial blood Pco2 levels. Explain, and be sure to include which<br>variable(s) of Fick's law are altered.<br>

Extracted text: Coal miners inhale large quantities of fine coal dust when they are working in the mines. Over the years, the dust irritates their alveolar surfaces resulting in inflammation and then development of scar tissue (a tough, stiff, thick, fibrous tissue) within the lung walls. Answer the following questions based on a coal miner who has developed very extensive and severe scar tissue in their lungs. 1. Define compliance. 2. Would coal miners have high or low lung compliance? Explain. 3. What happens to the skeletal muscle force required to generate a normal TV? 4. Given your answer to #3, with this very severe situation, can skeletal muscle continue indefinitely to generate the required force? Why or why not? And if not, then what change in TV occurs? 5. Explain what happens to alveolar ventilation. 6. What happens to arterial blood Po2 levels? Explain, and be sure to include which variable(s) of Fick's law are altered. 7. What happens to arterial blood hemoglobin saturation (% HbO2)? Explain. 8. What happens to arterial blood Pco2 levels. Explain, and be sure to include which variable(s) of Fick's law are altered.

Jun 11, 2022
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