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Assignment 12ISYE695 Graduate Seminar40 Points Do this assignment completely on your own. Do not wait until the day the assignment is due to clarify any questions you may have. Review the presentation with audio on “Responsible Conduct of Research” and read the book “Introduction to the Responsible Conduct of Research (RCR)” linked to the External Links section of the course Blackboard site. After reading the book, think about each case scenario in this assignment, see the sample answer provided for a sample scenario, identify which core area(s) of RCR each given scenario falls under, come up with appropriate answers, and type your own best answer for each scenario for items (a) through (d). Remember to include in your answers, the scenario number and the question numbers. Type your answers as detailed (not just a few words or phrases or just yes or no answers), complete, and coherent sentences, and proofread your answers for spelling and grammar before submitting them in a Word file as mentioned in assignment instructions. Follow the writing guidelines given for previous homework assignments, and use 1-inch margins on all four sides of the page, Times New Roman 12-point black font for text, 0 pt Before and After line spacing, single-line spacing, and one single-spaced blank line between paragraphs and answers. For each scenario, answer the following questions, and include the identifiers (a), (b), (c), and (d) with your answers for each question so that your answers for particular items can be identified and graded easily. a) Describe the major dilemmas or potential problems/issues you see in the scenario with respect to Responsible Conduct of Research. b) Which of the 9 core area(s) of Responsible Conduct of Research mentioned in the course materials, the scenario falls under and why? Each scenario may fall under multiple areas. c) Explain what you would do to resolve the dilemmas/problems/issues constructively for everyone involved. (Think about who you can talk to and get clarifications, what the options are, what are the consequences for those options, etc., and do not think of just yes or no answers or say you would walk away from the situation, quit, etc.) d) Explain what you can do proactively before such a dilemmas/problems/issues arise in the future in your work. Scenario #1 You and another student are working as a team on a research project to study alcohol consumption by college students and its impact on their studies. You both have already received approval from IRB (Institutional Review Board) for the Informed Consent Form and the survey you have designed to conduct surveys of students’ alcohol drinking habits, and are planning to send out the survey the next day to potential student recipients. A third student, who is your good friend, wants to join your project team late, conduct a survey of students’ eating habits for another project, and add the other project’s survey questions to your survey. The third student says the additional survey questions on students’ eating habits are less intrusive than your survey questions on alcohol consumption and does not see the need for IRB approval again for the informed consent form and the additional questions as the same students will be responding to the additional questions too. Scenario #2 You are pursuing your thesis research and your research work in the department’s laboratory is going well. Late one afternoon another graduate student, who works in the same research laboratory, hands you the draft of a research paper written by your thesis advisor (faculty) and ready to be submitted to a journal for publication. Your thesis advisor is the faculty member in charge of the laboratory who drafted the paper and gave it to the other graduate student to proof-read it before the paper is finalized and submitted to a journal for publication. The other graduate student has circled a graph in your thesis advisor’s draft paper and indicates the graph does not appear to represent the results from an experiment conducted in the laboratory. After checking the graph carefully and reviewing the supporting data, you also think that the results shown on the graph in the draft paper do not appear to represent the results from the experiment correctly. Scenario #3 You and another graduate student are working on a biomedical project involving rabbits for which your faculty advisor has obtained approval from the university’s IACUC. You and the other graduate student are scheduled daily to take turns to feed the rabbits, administer them the required dosages of medication, and record relevant observations in the lab note book, which is secured in the lab for only the two of you to access. One weekend when you come into the lab for your turn to feed the rabbits, administer the medication record observations, you find the other graduate student feeding the rabbits. When you ask the other graduate student what was going on, the other student admits to waking up late, missing the research schedule, and thus doing things later than scheduled. The other graduate student argues that it was not a big deal and that the data from the current feeding of the rabbits, administered medication and relevant observations would be recorded in the lab notebook and would still be usable data, and that you need not worry, could go home, and pick up your turn the next day. Scenario #4 You agree to pursue a thesis under the supervision of a faculty member who has an externally funded project on the thesis topic. The funded project is expected to last 12 months and you anticipate completing your thesis by that time also. The faculty member offers you a research assistantship with a tuition waiver and a stipend, and spends the first semester teaching you about the project topic and what you are expected to do for the project during the remaining months of the project. Six months into the project, you receive a really good job offer that pays much more than the research assistantship and the job does not require you to complete the thesis. You think a job like that may not be offered to you again if you wait to complete the thesis and the degree. Scenario #5 You ask your faculty advisor for a summer research project and your advisor offers you a job to conduct some independent clinical trials by your university for a biomedical research project for a pharmaceutical company. You are excited about this learning opportunity and begin working on the project. You return home one weekend and during dinner, you parents ask you about your summer job. You mention that you are conducting independent clinical trials for a biomedical project and your father suddenly seems very interested in your project. He says, “It is one of our subsidiary companies that has funded your university lab to conduct those independent clinical trials. I hope you do a good job on the project because the company needs that drug to be proven successful to get a win for the shareholders and for those who need the drug.” Sample Scenario You, Pat, and Drew work at different universities, share a common interest in improving employee working conditions but come from different engineering backgrounds. You are in industrial and systems engineering and work in biomechanics, and is new to research. Pat is in electrical engineering and works on computer engineering technology. Drew is in mechanical engineering and works on designing devices and mechanisms. The three of you start to work on a project that could improve working conditions for shop floor employees handling heavy equipment. The research objectives and methodologies quickly fall into place and you are ready to conduct experiments and collect data. You mention the need for IRB approval from all three universities before proceeding with the project as it is a human factors project. Pat and Drew suggest that you handle it at your university as you deal with human factors and they would like to continue working on the project. They see you as a hurdle in stopping the project for IRB approval. Sample Answer for the Sample Scenario (Note: This is just a sample answer to give you an idea on how to write your answer and this is not necessarily the answer or the best answer) a) Describe the major dilemma or potential problem/issue you see in the scenario. The major dilemmas are that I do not want to continue working on the project without IRB approval from all three universities but the other two want to continue, and there could be other disagreements like these in the future. These two issues will have to be addressed before continuing with the project. b) Which core area(s) of Responsible Conduct of Research the scenario falls under and why? This scenario falls under (1) Human Subjects research as it involves improving working conditions for humans and will potentially require testing the ideas with human subjects, and (2) Collaborative Science as the project is being done collaboratively by three researchers in three different universities and will potentially bring in some concerns, conflicts and issues. c)Explain what you can do to resolve the dilemma/issue constructively for everyone involved. The first thing to do with any dilemma is to get all the facts related to an issue and get clarifications as our understanding of issues could be incorrect, and in some cases the policies and procedures could have changed recently. I will deal with the first dilemma about getting IRB approval from all three universities by discussing the details of the project with the Office of Research Compliance at my university. I will seek clarifications from my university if my understanding that IRB approval is certainly needed from all three universities, and if that is the clarification I receive, I will share that with my project collaborators, and request them to get clarifications from their universities also. I will do my best to explain to them the potential for injury to human subjects and the liabilities involved in such actions. If my collaborators agree and get the same clarification from their universities, then the issue is resolved and we can work on preparing the paperwork for obtaining IRB approval. If my collaborators do not agree that they should seek clarifications on getting IRB approval from their universities then I may have several options: (i) I can withdraw from the project, save what I have contributed so far on the project, and decide to collaborate with others who would comply with IRB approval policies. (ii) I can ask the other two collaborators what their specific concerns are about seeking IRB approval from their universities for the project as the paperwork will be the same for all three universities, try to resolve their concerns amicably, and proceed with getting IRB approval from all three universities and continue with the project. Sometimes getting all the facts and clarifying concerns may resolve a dilemma. (iii) If the other two collaborators do not want to seek IRB approval from their universities because they think what they have to do for the project does not directly involve human subjects then I can go back to the Office of Research Compliance at my university and ask