Calculate the oral loading dose (LD) of digoxin for Miss Jones who weighs 60 kg. The desired plasma concentration (Cp) is 1.5 mcg/L, volume of distribution (Vd) is 7.3 L/kg, the salt factor (S) is 1...

Calculate the oral loading dose (LD) of digoxin for Miss Jones who weighs 60 kg. The

desired plasma concentration (Cp) is 1.5 mcg/L, volume of distribution (Vd) is 7.3 L/kg, the

salt factor (S) is 1 and bioavailability fraction (F) is 0.7.
Give your answer to the nearest whole number of micrograms.


The equation below can be used:
Loading Dose = Cp desired x Vd
S x F