BIOL121 ASSIGNMENT 3: Written assessmentScenario: EshmaEshma is a 42-year-old marathon runner, who has presented to her GP clinic after completing a training run.She runs...

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BIOL121 ASSIGNMENT 3: Written assessment
Scenario: Eshma























Eshma is a 42-year-old marathon runner, who has presented to her GP clinic after completing a training run.
She runs four to five times per week and does yoga or Pilates on the other days. Eshma has experienced
light-headedness and significant muscle pain after her last three runs. Whilst talking to the clinic nurse,
Eshma admits to feeling lethargic and like her “heart is racing”. She has also been a little unsteady on her
feet and stumbled climbing the stairs in her home the previous evening. She reveals that, although she is still
eating well and drinking adequate fluids, her caloric intake has been less than usual. She has lost 2 kg in the
last month, and her last period was 5 months ago. Blood and urine tests ruled out pregnancy as a cause of
amenorrhea.






Eshma applied Voltaren Emulgel, a topical non-steroidal anti-inflammatory drug (NSAID), to her quadriceps
and calves immediately after this morning’s run, hoping to relieve some of her muscle soreness.






A medical history was taken, and urinalysis conducted, identifying the following:


















Height


















Weight


















Appearance


















Temperature


















Blood Group


















HR


















BP


















Respiratory rate


















Diet
























































Body composition


















Past patient history


















Torn meniscus in right knee, surgically
repaired; one caesarean delivery 14
years ago. Takes fish oil and calcium
supplements. Relies upon barrier
methods for contraception.





















Social status






Urinalysis






Colour
Blood






Bilirubin
Urobilinogen
Ketone
Protein
Nitrite
Glucose






pH
Specific Gravity
Leucocytes












173 cm
61 kg
Pallor, dark circles under eyes
38.6


C
O-
86 bpm
87/58 mm Hg
25 bpm
High protein, high intake of fruit and
vegetables; High carbohydrate after
marathon
Low body fat






Married with two teenage children.






S
traw coloured


-
-
0.2 mg/dL






+
++
-
-
5.5
1.015
-






























































©ACU 2022












1


























All topics and their key points listed below must be discussed in your essay






Topic 1: Reproduction (10 marks total)






Endometrial tissue contains glandular structures relevant to Eshma’s reproductive function. Explain the role
of this glandular tissue in reproductive function, including any likely changes from normal in the secretion
and resultant effects for Eshma. (4 marks)






Considering Eshma and her current circumstances, describe the role of oestrogen and explain whether you
expect her oestrogen levels to be different to normal. Your discussion should include the homeostatic
regulation of female reproductive physiology and the relevant glands and hormones. (6 marks)






Topic 2: Respiratory system (5 marks total)






Describe the changes in volume and pressure that will be occurring in Eshma’s chest cavity during exhalation
on a long run. Explain why these changes are occurring, and the effect upon airflow. (5 marks)






Topic 3: Digestion/metabolism (8 marks total)






Eshma supplements her diet with a daily protein shake after exercise. Today though, Eshma is experiencing
some discomfort with indigestion, so takes a dose of Gaviscon® Dual Action soon after drinking her shake.
Discuss how taking Gaviscon® Dual Action could affect digestion of the protein in her shake. (4.5 marks)






State the hormone that is MOST active in maintaining Eshma’s blood glucose levels during a marathon.
Explain your answer. (3.5 marks)






Topic 4: Pharmacology (7 marks total)






In the past Eshma has used

Voltaren Emulgel

(containing an NSAID) to ease her aching muscles after
exercise. However, a friend has mentioned that Voltaren is also available in tablet form and may be better
for the “task”.






Compare and contrast the two different formulations of Voltaren available to Esham. In your answer you will
need to examine the following: (7 marks)












  • Where the drug is likely to be absorbed in each form












  • Likely bioavailability of each form and susceptibility to hepatic first pass effect












  • Why would the oral form be better?
















Answered Same DayOct 26, 2022

Answer To: BIOL121 ASSIGNMENT 3: Written assessmentScenario: EshmaEshma is a...

Dr. Sulabh answered on Oct 26 2022
59 Votes
CASE STUDY 1
Name of the Student
Name of the Course
Name of the teacher or professor
Date
Assignment
Topic 1
In the presen
t case study due to overage, this patient is suffering from menopausal problems. Eshma is a marathon runner and she regularly performs exercises to keep her fit. Recently she experienced a tear in the meniscus region of the knee leading to serious pain. The blood pressure of this patient is less as revealed in this study. As age advances, there is a drop in the levels of the female hormones secreted by the body like estrogen and progesterone. The uterus lining and the follicular egg present in the ovary are nourished by the secretion of female hormones like estrogen and progesterone. Follicle-stimulating hormone and the luteinizing hormone maintain the layer of the endometrial lining in the ovary with proper nourishment (Kelleher et al., 2019).
The old endometrial layer is shed and a new layer develops as a female undergoes the monthly menstrual cycle. She is presently suffering from an amenorrhea problem and she was able to menstruate previously last time 5 months ago (Kelleher et al., 2019). The menstrual cycle consists of the 3 stages namely the proliferative, secretory, and degeneration stage which is disrupted during the menopausal or amenorrhea stage. 
The levels of estrogen hormone will be low in this patient named Eshma in comparison to the level of this hormone estrogen present in a normal female who is young and healthy (Paxton et al., 2019). The secretion of the follicle-stimulating hormone and luteinizing hormone causes the development of the ovarian follicles leading to the release of the egg from the ovary. The FSH and LH are released from the pituitary gland and the release of the gonadotropin-releasing hormone from the hypothalamus provides the stimulus for the secretion of these hormones. The hormone estrogen is secreted by the ovaries required for the growth and development of female sexual characteristics (Lumen Learning, 2020). Further the endometrium glands present in the ovary are filled with glycogen to provide a rich source of energy and nutrition to the growing follicle cells during the secretory phase of the menstrual cycle (Paxton et al., 2019). Thus homeostasis and feedback regulation of the hormones is maintained in the females. There is the presence of ketone bodies in the urine of this patient which indicates that she is suffering from...
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