Aspirin is a reversible inhibitor of cyclo-oxygenase type 1 (COX-1).
1. Aspirin inhibits platelet aggregation at doses below those needed for an anti-inflammatory effect.
2. Fibrinolytic infusions of recombinant tissue-type plasminogen activator (rt-PA; alteplase) for myocardial infarction are usually given over the course of 1 hour, whereas streptokinase is given for 3–24 hours.
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