As part of a downstream processing sequence, 10 m³ of a process fluid containing 20 kg m-3 of an enzyme is to be concentrated to 200 kg/m³ by means of ultrafiltration. Tests have shown that the enzyme...

Extracted text: As part of a downstream processing sequence, 10 m³ of a process fluid containing 20 kg m-3 of an enzyme is to be concentrated to 200 kg/m³ by means of ultrafiltration. Tests have shown that the enzyme is completely retained by a 10,000 MWCO surface-modified polysulphone membrane with a filtration flux given by: J = 0.04 In(250/C;) where J is the flux in m/h and C, is the enzyme concentration in kg m-3. Four hours is available for carrying out the process. (a) Calculate the area of membrane needed to carry out the concentration as a simple batch process, (b) Use the following approximation for estimating the average flux during a simple batch process: Jav J; +0.27(J; – J;) -