Anticoagulation with warfarin and antiplatelet therapy with aspirin are equal first-choice drugs for the
secondary prevention of recurrent ischaemic strokes in the presence of sinus rhythm.
1. Cerebral ischaemia depolarises neurons and causes the release of large amounts of glutamate.
2. Donepezil is an acetylcholinesterase inhibitor with selectivity for the CNS.
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