An otherwise healthy 9-year-old boy has a mass growing below his knee. At surgery, the mass is removed and sent to the pathology department. Sheets of hyperchromatic cells with small round blue nuclei...

An otherwise healthy 9-year-old boy has a mass growing below his knee. At surgery, the mass is removed and sent to the pathology department. Sheets of hyperchromatic cells with small round blue nuclei are seen under the microscope. Cytogenic analysis reveals a t(11;22) translocation. What is the most likely diagnosis?

A. Osteosarcoma

B. Multiple myeloma

C. Giant cell tumor

D. Metastatic disease

E. Ewing sarcoma