An epidemiologist found five cases of “big toe cancer” in the Yukon Territory. Because there were only a few cases, the epidemiologist decided to conduct a matched case-control study to determine...


An epidemiologist found five cases of “big toe cancer” in the Yukon Territory. Because there were only a few cases, the epidemiologist decided to conduct a matched case-control study to determine whether shoe size larger than 9 is a risk factor for big toe cancer. Cases were individually matched to one control for daily activity, history of athlete’s foot, and history of ingrown toenails. The following data were gathered:




Shoe size > 9

Pair Case Control
  1     Yes      No
  2      No       No
  3      No      Yes
  4     Yes     Yes
  5      No      Yes


  1. Compute the proper measure of association.

  2. Interpret your results.

  3. If you were to investigate a rare cancer in Lynchburg, where might you look for data?

  4. What would be necessary legally and ethically to be able to utilize this data set(s)?



Jun 02, 2022
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