An adult male patient (52 yr, 75kg) whose serum creatinine is 2.4mg% is to be given gentamicin sulfate for a confirmed gram-negative infection. The usual dose of gentamicin in adult patients with normal renal function is 1 mg/kg every 8 hrs by multiple IV bolus injections. Gentamicin sulfate (Garamycin®) is available in 2-mL vials containing 40 mg gentamicin sulfate per mL. Calculate:a. The creatinine clearance in this patient by the Cockcroft and Gault method andb. The appropriate dosage regimen of gentamicin sulfate for this patient in mg and mL.

An adult male patient (52 yr, 75kg) whose serum creatinine is 2.4mg% is to be given gentamicin sulfate for a confirmed gram-negative infection. The usual dose of gentamicin in adult patients with...

An adult male patient (52 yr, 75kg) whose serum creatinine is 2.4mg% is to be given gentamicin sulfate for a confirmed gram-negative infection. The usual dose of gentamicin in adult patients with normal renal function is 1 mg/kg every 8 hrs by multiple IV bolus injections. Gentamicin sulfate (Garamycin®) is available in 2-mL vials containing 40 mg gentamicin sulfate per mL. Calculate:

a. The creatinine clearance in this patient by the Cockcroft and Gault method and

b. The appropriate dosage regimen of gentamicin sulfate for this patient in mg and mL.

Jun 06, 2022