Although beta-blockers are traditionally contraindicated in heart failure secondary to systolic dysfunction, this class of medications is considered beneficial in diastolic dysfunction. The...

Although beta-blockers are traditionally contraindicated in heart failure secondary to systolic dysfunction, this class of medications is considered beneficial in diastolic dysfunction. The modification of which parameter does not contribute to the beneficial effects of beta-blockers in diastolic dysfunction?

A. Increasing diastolic filling time

B. Decreasing myocardial oxygen demand

C. Improved LV filling secondary to improved relaxation

D. Decreasing risk of myocardial ischemia

E. Increasing LV outflow gradient