Agonist Lipid bilayer B G G АТР active CAMP PDE ÞAMP Phosphorylation of target proteins РКА active The illustration shows a G protein coupled receptor (GPCR) linked to a second messenger signalling...


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Agonist<br>Lipid bilayer<br>B<br>G<br>G<br>АТР<br>active<br>CAMP<br>PDE<br>ÞAMP<br>Phosphorylation of<br>target proteins<br>РКА<br>active<br>The illustration shows a G protein coupled receptor (GPCR) linked to a second<br>messenger signalling pathway. The activated G protein causes an increase in<br>levels of CAMP.<br>(a) What is the name of the enzyme labelled as B?<br>(b) GPCRS can couple to different G proteins. Which class, from the<br>options Ga, G., G or G12/13, is the receptor shown here?<br>Explain where signal amplification can occur in this second<br>messenger pathway<br>(c)<br>

Extracted text: Agonist Lipid bilayer B G G АТР active CAMP PDE ÞAMP Phosphorylation of target proteins РКА active The illustration shows a G protein coupled receptor (GPCR) linked to a second messenger signalling pathway. The activated G protein causes an increase in levels of CAMP. (a) What is the name of the enzyme labelled as B? (b) GPCRS can couple to different G proteins. Which class, from the options Ga, G., G or G12/13, is the receptor shown here? Explain where signal amplification can occur in this second messenger pathway (c)

Jun 11, 2022
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