Aggressive fluid resuscitation of critically ill patients (including those who sustain traumatic injury) with crystalloid solutions can have negative effects of interstitial edema, compromising tissue...

Aggressive fluid resuscitation of critically ill patients (including those who sustain traumatic injury) with crystalloid solutions can have negative effects of interstitial edema, compromising tissue perfusion and requiring higher volumes of solution for resuscitation. Colloid solutions have also been used in resuscitation. There is ongoing debate about the effectiveness of using colloid solutions compared with crystalloid solutions for effective resuscitation and tissue perfusion