ACE inhibitors may cause cough by reducing the synthesis of bradykinin. 1. Survival in chronic heart failure is improved by β-adrenoceptor antagonists. 2. Hydralazine is a vasodilator with a...

ACE inhibitors may cause cough by reducing the synthesis of bradykinin.

1. Survival in chronic heart failure is improved by β-adrenoceptor antagonists.

2. Hydralazine is a vasodilator with a predominant effect on veins.

3. Natriuretic peptides are synthesised by neprilysin.

4. Sacubitril valsartan is no more effective than an ACE inhibitor in heart failure with reduced ejection fraction.