. A whole genome of 150Mb is to be sequenced. A small-plasmid library (average insert size 3 kb) providing 5× insert coverage ( = clone coverage) and a BAC library (average insert size 150 kb)...

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A whole genome of 150Mb is to be sequenced. A small-plasmid

library (average insert size 3 kb) providing 5× insert coverage ( = clone coverage)

and a BAC library (average insert size 150 kb) providing 15× insert

coverage are prepared for sequencing. If sequencing reads of length 700 nt are

generated from both ends of all inserts in both libraries, compute the average

sequence read coverage for the genome.