A research team interested in mapping human genes discovered a new restriction length polymorphism (RFLP). a. First, they test the RFLP in a family with the pedigree below. The individuals colored...

Extracted text: A research team interested in mapping human genes discovered a new restriction length polymorphism (RFLP). a. First, they test the RFLP in a family with the pedigree below. The individuals colored blue are affected by hemophelia, a blood clotting disease. Dad Mom daughter1 daughter2 son1 son1 On what chromosome is the RFLP found? Explain your answer. b. Next, they genotyped (determined the RFLP polymorphism, type 1 or type 2) of daughterl's family with the results shown below: husband daughter1 %3D Are the RFLP and the hemophilia gene linked? Explain your reasoning.


Extracted text: c. Finally, the research team genotyped hundreds of families affected by haemophilia. Among those families, they found many that had a pattern of RFLP like that of daughter1, her husband and her parents. When they genotyped the children in those families, they found the following association between the RFLP and hemophilia: 458 46 54 442 The numbers at the bottom indicate the number of progeny with that combination of hemophilia phenotype and RFLP polymorphism found among these families. What is the map distance between the RFLP and the hemophilia gene? Show your work. (hint: think about how this pedigree is similar to the gene mapping experiment with black and vestigial fruit flies)