A population of mice will be used in a dose response study using chemical A. One in vitro study revealed that 100 ppm of A in a mice body might correspond to the LD50. If the average body mass for the...

A population of mice will be used in a dose response study using chemical A. One in vitro study revealed that 100 ppm of A in a mice body might correspond to the LD50. If the average body mass for the mice population is 200 g: -Calculate the estimated LD50 in mg per kg of mouse body mass. -If the range of doses goes from 20% to 2 times the estimated LD50 minimum and maximum bodily doses required in mg/kg of body mass, calculate the minimum and maximum bodily doses required in mg/ kg of body mass. -What are the minimum and maximum masses of A that must be injected to the mice?

Jun 05, 2022
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