A plant-scale experiment is being designed to compare the effects of a number of changes in reaction conditions (temperature, pressure, catalyst concentration, regeneration frequency, and throughput)...

A plant-scale experiment is being designed to compare the effects of a number of changes in reaction conditions (temperature, pressure, catalyst concentration, regeneration frequency, and throughput) on the yield of ethylene glycol via the du Pont process. Because of the various process lags involved, considerable quantities of raw materials will be used. Give two general design approaches to this problem and discuss them as you would with the production superintendent.