A patient describes to you a family history of a disease. She has it, as does her father and grandfather. Several uncles and aunts also have this disease, as does her sister. She has another sister...

A patient describes to you a family history of a disease. She has it, as does her father and grandfather. Several uncles and aunts also have this disease, as does her sister. She has another sister and brother who do not have the disease. She worries that she will pass this disease on to her own children. What is the inheritance pattern if this disease is monogenic, and what is the likelihood that her daughter also has this familial disease?

A. Autosomal dominant, 25%

B. Autosomal recessive, 25%

C. X-linked recessive, 100% in boys

D. Autosomal dominant, 50%