A couple in their early 30s give birth to an infant who dies within an hour of delivery. Pathologic analysis of the infant indicates trisomy 13. The couple undergoes chromosomal analysis. and the...

A couple in their early 30s give birth to an infant who dies within an hour of delivery. Pathologic analysis of the infant indicates trisomy 13. The couple undergoes chromosomal analysis. and the father is found to have a balanced translocation of chromosomes 13 and 21.The couple asks whether this problem is related to their ages and what risk they might have for having another child with trisomy 13.

1. Is this problem age-related?

2. Does this couple have an increased risk for having another child with trisomy 13?

3. What other pregnancy outcomes are possible for this couple?