A client who is taking an anticoagulant states, I wake up every morning with arthritis pain and I always take aspirin or ibuprofen. The nurse s response would be based on which of the following physiologic concepts?
1. Aspirin and ibuprofen (Motrin) will counteract the therapeutic effects of many anticoagulants.
2. Anticoagulants will reduce the half-life of drugs such as aspirin and ibuprofen.
3. Many substances such as aspirin and ibuprofen will increase the risk of bleeding.
4. The combination of aspirin products with anticoagulants will worsen arthritis pain.
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