A client who has duodenal ulcers is receiving long-term therapy with ranitidine (Zantac). The nurse includes in the care plan that the client should be monitored for which of the following adverse effects?
1. Photophobia and skin irritations
2. Neutropenia and thrombocytopenia
3. Dyspnea and productive coughing
4. Urinary hesitation and fluid retention
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