A client has been taking imipramine (Tofranil) for depression for 2 days. His sister asks the nurse, “Why is he still so depressed?” Which of the following responses by the nurse is most appropriate?...

A client has been taking imipramine (Tofranil) for depression for 2 days. His sister asks the nurse, “Why is he still so depressed?” Which of the following responses by the nurse is most appropriate?

1. “Your brother is experiencing a very serious depression.”

2. “I'll be sure to convey your concern to his physician.”

3. “It takes 2 to 4 weeks for the drug to reach its full effect.”

4. “Perhaps we need to change his medication.”