A blood sample taken from a 247 Ib patient 6 hours after heparin therapy is initiated shows an aPTT of 32 seconds. Calculate the infusion rate, in mL/hr, according to the heparin protocol below....

The answer key is 24.5 mL/hr. Please show step by step solution.

90 seconds Hold infusion for 1 hour; when restarted, decrease infusion rate by 3 units/kg/h "/>
Extracted text: A blood sample taken from a 247 Ib patient 6 hours after heparin therapy is initiated shows an aPTT of 32 seconds. Calculate the infusion rate, in mL/hr, according to the heparin protocol below. |Standard Heparin IV Premixed Solution is 25,000 units in 250 mL (100 units per mL) Initial laboratory tests (draw before starting heparin): APTT, PT, CBC with platelet count Day 2 and every 3 days thereafter: CBC with platelet count APTT six (6) hours after heparin infusion is started Bolus Dose None 80 units/kg (limit 8000 units) -ADULT WEIGHT-BASED HEPARIN PROTOCOL- Other (specify: units) Continuous infusion rate aPTT six (6) hours after every change in heparin administration rate or bolus dose of heparin Once a therapeutic APTT level is reached, do an aPTT six (6) hours later After two (2) consecutive therapeutic aPTT levels are obtained, do an aPTT daily at 0600 Discontinue all IM medications and other IM injections 18 units/kg/h Other (specify:" units/h) APTT Value Heparin Dose Adjustments <35 seconds="" bolus="" with="" 80="" units/kg="" and="" increase="" infusion="" rate="" by="" 4="" units/kg/h="" 35="" to="" 45="" seconds="" bolus="" with="" 80="" units/kg="" and="" increase="" infusion="" rate="" by="" 2="" units/kg/h="" 46="" to="" 70="" seconds="" no="" change="" in="" infusion="" rate="" 71="" to="" 90="" seconds="" decrease="" infusion="" rate="" by="" 2="" units/kg/h="">90 seconds Hold infusion for 1 hour; when restarted, decrease infusion rate by 3 units/kg/h