A ‘‘drug patch’’ is designed to slowly deliver a drug (species A) through the body tissue to an infected zone of tissue beneath the skin. The drug patch consists of a sealed reservoir containing the...


A ‘‘drug patch’’ is designed to slowly deliver a drug (species A) through the body tissue to an infected zone of tissue beneath the skin. The drug patch consists of a sealed reservoir containing the drug encapsulated within a porous polymer matrix. The patch is implanted just below the skin. A diffusion barrier attached to the bottom surface of the patch sets the surface concentration of the drug in the body tissue at 2 mol/m3, which is below the solubility limit. The mean distance from the drug patch to the infected area of tissue is 5 mm. To be effective, the drug concentration must be at least 0.2 mol/m3
at the top edge of the infected zone. Determine the time it will take in hours for the drug to begin to be effective for treatment. The effective molecular diffusion coefficient of the drug through the body tissue is
.

Nov 23, 2021
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