A 74-year-old Caucasian woman presents for a routine physical and is found to be anemic. Her colonoscopy a year ago was normal, and additional laboratory tests confirm that she is not iron deficient....


A 74-year-old Caucasian woman presents for a routine physical and is found to be anemic. Her colonoscopy a year ago was normal, and additional laboratory tests confirm that she is not iron deficient. Serum protein electrophoresis demonstrates a protein spike, and her kidney biopsy microscopically demonstrates a translucent, smooth, glassy material. Multiple myeloma is diagnosed. What is the etiology of her amyloidosis?


A. Hereditary amyloidosis


B. Misfolded mutant proteins


C. Reactive systemic amyloidosis


D. Light chain amyloidosis



May 06, 2022
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