A 65-year-old African American male comes to the clinic complaining of bone pain and fatigue. Incidentally, he notes a recent change in urination. A urinalysis reveals Bence-Jones proteins and a skull...

A 65-year-old African American male comes to the clinic complaining of bone pain and fatigue. Incidentally, he notes a recent change in urination. A urinalysis reveals Bence-Jones proteins and a skull X-ray shows punched out lesions. What is your diagnosis?

A. Waldenström macroglobulinemia

B. Multiple myeloma

C. Monoclonal gammopathy of undetermined significance

D. Lymphoplasmacytic lymphoma