A 65-kg man is participating in a research study for which it is necessary to know the volumes of his body fluid compartments. To measure these volumes, the man is injected with 100 mCi (millicurie)...


A 65-kg man is participating in a research study for<br>which it is necessary to know the volumes of his body<br>fluid compartments. To measure these volumes, the<br>man is injected with 100 mCi (millicurie) of H20 and<br>500 mg of mannitol. During a 2-hour equilibration<br>period, he excretes 10% of the H,0 and 10% of the<br>mannitol in his urine. Following equilibration, the<br>concentration of H,0 in plasma is 0.213 mCi/100 mL<br>and the concentration of mannitol is 3.2 mg/100 mL.<br>What is his total body water, his ECF volume, and his<br>ICF volume? Is the man's total body water appropriate<br>for his weight?<br>

Extracted text: A 65-kg man is participating in a research study for which it is necessary to know the volumes of his body fluid compartments. To measure these volumes, the man is injected with 100 mCi (millicurie) of H20 and 500 mg of mannitol. During a 2-hour equilibration period, he excretes 10% of the H,0 and 10% of the mannitol in his urine. Following equilibration, the concentration of H,0 in plasma is 0.213 mCi/100 mL and the concentration of mannitol is 3.2 mg/100 mL. What is his total body water, his ECF volume, and his ICF volume? Is the man's total body water appropriate for his weight?

Jun 11, 2022
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