A 58-year-old woman with a long history of iron deficiency anemia now presents with progressive dysphagia (difficulty swallowing), primarily with solid foods. On exam she has a swollen, painful, smooth-appearing tongue (glossitis) and spooning of her nails (koilonychia). Endoscopy reveals she has a large esophageal web, which has been obstructing food passage. Her most likely diagnosis is:
A. Fanconi anemia
B. Lead poisoning
C. Esophageal cancer
D. Plummer-Vinson syndrome
E. Porphyria
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