A 42-year-old G3P1 presents with vaginal bleeding and is concerned she may have endometrial cancer. Her past gynecologic history is significant for a vaginal delivery of an infant with a neural tube defect 13 years ago, a first trimester miscarriage 10 years ago, and a ruptured ectopic pregnancy for which she underwent surgery 4 years ago. Her β-hCG level is elevated, but you cannot visualize a fetus or a snow storm pattern on ultrasonography. The patient is diagnosed with PSTT and undergoes successful hysterectomy. Which of the following are considered risk factors for GTD?
A. Age younger than 20 or older than 40 years
B. Diets low in beta-carotene and folic acid
C. History of prior molar pregnancy
D. Women with blood type A married to men with blood type O
E. All of the above
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