A 40-year-old patient presents with a hormone-secreting pituitary adenoma. Biopsy of the tumor shows proliferation of a single type of acidophilic cells. Which of the following signs and symptoms are most likely?
A. Hypertension, obesity, diabetes
B. Heat intolerance, weight loss, tachycardia
C. Inability to breast-feed, menorrhagia, headache
D. Enlarged jaw, diabetes, increased hand size
E. Polyuria, increased thirst, low urine-specific gravity
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