A 33-year-old, 70-kg woman remains lethargic after surgery for removal of an ovarian cyst. She has no other health problems. She was given 2.5 L of 0.45% saline during her operation and recovery. Her serum sodium is 122 mEq/L. How many milliequivalents of sodium are needed to raise her sodium to 130 mEq/L and how fast should it be replaced?
A. 200 mEq, 10 hours
B. 336 mEq, 16 hours
C. 448 mEq, 40 hours
D. 513 mEq, 20 hours
E. No replacement is needed
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