A 28-year-old female presents with an 8-month history of bloody diarrhea, intermittent crampy abdominal pain, persistent spasms of the bowel, and stringy mucus in her stools. You suspect IBD, with the likely diagnosis of UC. Which of the following will allow you to differentiate it from Crohn disease?
A. Areas of affected and unaffected mucosa, “skip” lesions
B. Transmural involvement on biopsy
C. Involvement of the small bowel
D. Pseudopolyps
E. Fistula formation
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