A 17-year-old boy with deafness and near-blind vision is referred to a research nephrologist by his primary care doctor, who is concerned about the microscopic hematuria discovered during a routine...


A 17-year-old boy with deafness and near-blind vision is referred to a research nephrologist by his primary care doctor, who is concerned about the microscopic hematuria discovered during a routine physical exam. His father was also deaf but was adopted, so no other family history is available. This nephrologist has easy access to electron microscopy and finds splitting of a thick GBM. What is the likely diagnosis?


A. Good pasture syndrome


B. Alport syndrome


C. Berger syndrome (IgA nephropathy)


D. Type IV lupus GN


E. Type I membranoproliferative GN



May 03, 2022
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