A 10-year-old boy with known HbSS disease presented to the Paediatric Emergency Department with a oneweek history of fever and severe pain in his right leg, severity 9/10 for the last two days. On...

A 10-year-old boy with known HbSS disease presented to the Paediatric Emergency Department with a oneweek history of fever and severe pain in his right leg, severity 9/10 for the last two days. On examination:
Pulse – 100 beats/min, BP – 110/70 mmHg, Capillary refill < 2sec="" and="" respiratory="" rate="" –="" 20="" breaths/="" min.="" he="" has="" point="" tenderness="" anteriorly="" on="" proximal="" tibia.="" there="" is="" no="" joint="">
X-ray of the affected limb shows marked periosteal elevation.
His complete blood count is: Hb – 6.5 g/dL WBC 30 x 10 /L Plt – 120 x 10 /L with a reticulocyte count of 1%.
Of the following the MOST appropriate management in this patient would be
a. Ibuprofen, Cefotaxime and top-up transfusion
b. Morphine, Ampicillin and hydration therapy
c. Morphine, Cefotaxime and hydration therapy
d. Morphine, Cefotaxime and top-up transfusion