4. Consider the now dominant variant of the SARS-CoV-2 called the D614G mutation: (A) (C) Spike Nucleocapsid Membrane S1 subunit S2 subunit Envelope 614 RNA viral genome NTD RBD FP HR1 HR2 TM CT (B)...


Genetics question about COVID-19.


what are the mRNA codon sequences of the

2019-dominant and 2020-dominant Spike proteins?


(how did you determine the actual sequence?)


4. Consider the now dominant variant of the SARS-CoV-2 called the D614G mutation:<br>(A)<br>(C)<br>Spike<br>Nucleocapsid<br>Membrane<br>S1 subunit<br>S2 subunit<br>Envelope<br>614<br>RNA viral genome<br>NTD<br>RBD<br>FP<br>HR1<br>HR2 TM CT<br>(B)<br>Binding site to ACE2<br>receptor in human cells<br>N terminal<br>domain<br>$1<br>Fusion<br>HR2<br>protein<br>S2<br>Transmembrane<br>domain and<br>cytoplasmic tail<br>Trends in Genetics<br>a) The mutation changes an Aspartate (D, Asp) to a Glycine (G, Gly) at nucleotide position 614<br>(that's why it's called the D614G mutant) in the S1 subunit of the Spike protein. Using only<br>the information above and a codon table, what are the mRNA codon sequences of the<br>2019-dominant and 2020-dominant Spike proteins? Note the figure above is not needed to<br>answer the question. Report in 5' to 3' orientation<br>

Extracted text: 4. Consider the now dominant variant of the SARS-CoV-2 called the D614G mutation: (A) (C) Spike Nucleocapsid Membrane S1 subunit S2 subunit Envelope 614 RNA viral genome NTD RBD FP HR1 HR2 TM CT (B) Binding site to ACE2 receptor in human cells N terminal domain $1 Fusion HR2 protein S2 Transmembrane domain and cytoplasmic tail Trends in Genetics a) The mutation changes an Aspartate (D, Asp) to a Glycine (G, Gly) at nucleotide position 614 (that's why it's called the D614G mutant) in the S1 subunit of the Spike protein. Using only the information above and a codon table, what are the mRNA codon sequences of the 2019-dominant and 2020-dominant Spike proteins? Note the figure above is not needed to answer the question. Report in 5' to 3' orientation

Jun 11, 2022
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