32 CHAPTER 3 Quantifying the Extent of TABLE TABLE 3-10 Alcohol Use and Outcome of Pregnancy Delivered Full Term Miscarriage 4 Chole 14 Heavy alcohol use me No heavy alcohol 46 36 Plac use ఈ TABLE...

a. Compute the relative risk of coronary artery disease in patients receiving the new cholesterol medication as compared to those receiving a placebo.

b. Compute the odds ratio of coronary artery disease in patients receiving the new cholesterol medication as compared to those receiving a placebo.

c. Which measure is more appropriate in this design, the relative risk or odds ratio? Justify briefly.

Extracted text: 32 CHAPTER 3 Quantifying the Extent of TABLE TABLE 3-10 Alcohol Use and Outcome of Pregnancy Delivered Full Term Miscarriage 4 Chole 14 Heavy alcohol use me No heavy alcohol 46 36 Plac use ఈ TABLE 3-11 Incident Coronary Artery Disease by Treatment Number with Number of Coronary Artery Participants Disease Cholesterol medication 400 28 Placebo 440 400 42 70 the first trimester of pregnancy and miscarriage. Fifty women who suffered miscarriage are enrolled, along with 50 who delivered full-term. Each participant's use of alcohol during pregnancy is ascertained. Heavy drinking is defined as four or more drinks on one occasion. The data are shown in Table 3-10. a. Compute the odds of miscarriage in women with heavy alcohol use during pregnancy b. Compute the odds of miscarriage in women with no heavy alcohol use during pregnancy.


Extracted text: TABLE 3-12 Total Follow-Up Time by Treatment Number with Total Follow-Up (years) Coronary Artery Disease Cholesterol 3451 28 medication 2984 42 Placebo c. Which measure is more appropriate in this design, the relative risk or odds ratio? Justify briefly. 5 In the study described in Problem 4, some patients were not followed for a total of 10 years. Some suffered rants (i e develoned co