30) A 45-year-old man is evaluated by his primary care physician for complaints of early satiety and weight loss. On physical examination,his spleen is palpable 10 cm below the left costal margin and...

30) A 45-year-old man is evaluated by his primary care physician for complaints of early satiety and weight loss. On physical examination,his spleen is palpable 10 cm below the left costal margin and is mildly terder to palpation. His laboratory studies show a leukocyte count of 125,000/Ml with a differential of 80% neutrophils, 9% bands, 3% myelocytes, 3% metamyelocytes,1% blasts, 1% lymphocytes, 1% eosinophils, and 1% basophils. Hemogicbin is 8.4 g/dL, hematocrit 26.8% ,and platelet count is 668,000/uL. A bone marrow biopsy demonstrates increased celluarity with an increased myeloid to erythroid ratio. Which of the following cytogenetic abnormalities is most likey to be found in this patient? A Deletion of a portion of the long arm of chromosome 5, del(5q) B Inversion of chromosome 16,inv(16) CReciprocal translocation between chromosomes 9 and 22 (Philadelphia chromosome D Translocations of the long arms of chromosomes 15 and 17 E Trisomy 12

Jun 09, 2022
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