20) Is the statement True or False? Chronic toxicity tests should be run during a period of 90 days for the test animals. 21) Sort the below given steps prior to in vivo tests of a biomaterial....

Extracted text: 20) Is the statement True or False? Chronic toxicity tests should be run during a period of 90 days for the test animals. 21) Sort the below given steps prior to in vivo tests of a biomaterial. Assurance of sterilized material preparation Appropriate computer simulation models Prerequisite material characterization tests Pertinent in vitro models 22) What are the 3R rules in in vivo test? 23) Clinical trials encompass 3 different phases as given below , match of the distinction for the extent of the trial for the phases ? Phase I Phase II Phase III biomaterial is tested on a small group реople (ca 60-80) comparison of the effectiveness of the new treatment, (ca 1000 – 3000) large group (ca 100-300)