1.Ms. A.S., age 31, has been diagnosed with systemic lupus erythematosus. She had her first signs and symptoms 2 years ago. At this time she is having an exacerbation, which includes a facial rash, joint pains, and chest pain. She also has protein in her urine, indicating a kidney abnormality.
(1) Explain the basic pathophysiology of this disease.
(2) Describe three factors that would assist in making the diagnosis.
(3) Describe the typical rash Ms. A.S. would have at this time.
(4) Her chest pain is due to inflammation of the pleural membranes. Explain why this pain would be more severe during inspiration.
(5) Her dose of prednisone, a glucocorticoid, has been increased. Briefly explain why she will return to a lower dose after the exacerbation ends.
(6) Explain why moderate exercise would be helpful.