2. Explain how the miR-200 family of miRNAs behave as tumorsuppressor genes. What happens when their expression is blocked or decreased?3. A protein called trypsin, which plays a role in digestion, is made by pancreatic cells and secreted from those cells. Starting with a sample of pancreatic cells, a researcher modified the gene that encodes trypsin by mutating the ER signal sequence so it was no longer recognized by SRP. How would this mutation affect the targeting of trypsin?
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