1.) Which of the following would be a good chemotherapy approach: blocking formation of the ribonucleotide GTP or blocking formation of the deoxyribonucleotide dGTP? Why?
Please explain the chemical differences between each of the two nucleotides. Use the specific processes below to support your choice by explaining how either GTP or dGTP are related to these and how loss of the particular molecule would affect each process.
A.) PEP carboxykinase in gluconeogenesis
B.) Succinyl-CoA synthetase in the TCA Cycle
C.) Glucagon signal transduction
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