1. What is a tautomeric shift? How does it cause mutations?
2. How is the mutation rate different from the mutation frequency?
3. Define triplet diseases and name their two main features.
4. Ethyl ethanesulfonate and nitrous acid are chemical mutagens. What does each do?
5. What is the difference between a substrate and a template transition mutation?
6. What types of mutations does UV light induce? List three mechanisms that can be used to repair the damage.
7. Discuss the mechanism of mismatch repair in E. coli.
8. Describe the role of the RecA protein in the SOS response.
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